• Benefit and risk assessment of fish in the Norwegian diet - Scientific Opinion of the Steering Committee of the Norwegian Scientific Committee for Food and Environment 

      Andersen, Lene Frost; Berstad, Paula; Bukhvalova, Barbara Alexandra; Carlsen, Monica Hauger; Dahl, Lisbeth Jane; Goksøyr, Anders; Sletting Jakobsen, Lea; Knutsen, Helle Katrine; Kvestad, Ingrid; Lillegaard, Inger Therese Laugsand; Mangschou, Bente; Meyer, Haakon Eduard; Parr, Christine Louise; Rakkestad, Kirsten Eline; Rasinger, Josef; Sengupta, Sayantan; Skeie, Guri; Starrfelt, Jostein; Ulven, Stine Marie (Research report; Forskningsrapport, 2022-06-07)
      In 2006, VKM published “A comprehensive assessment of fish and other seafood in the Norwegian diet”. The assessment supported the recommendation from Norwegian Health authorities to eat more fish both for dinner and on sandwiches. In an update of the assessment in 2014 VKM concluded that “the benefits from fish consumption clearly outweigh the negligible risk presented by current levels of ...
    • Coffee Consumption and Whole-Blood Gene Expression in the Norwegian Women and Cancer Post-Genome Cohort 

      Borgund Barnung, Runa; Nøst, Therese Haugdahl; Ulven, Stine Marie; Skeie, Guri; Olsen, Karina Standahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-09)
      Norwegians are the second highest consumers of coffee in the world. Lately, several studies have suggested that beneficial health effects are associated with coffee consumption. By analyzing whole-blood derived, microarray based mRNA gene expression data from 958 cancer-free women from the Norwegian Women and Cancer Post-Genome Cohort, we assessed the potential associations between coffee consumption ...
    • Effects of similar intakes of marine n-3 fatty acids from enriched food products and fish oil on cardiovascular risk markers in healthy human subjects 

      Kirkhus, Bente; Lamglait, Amandine; Eilertsen, Karl-Erik; Falch, Eva; Haider, Trond; Vik, Hogne; Hoem, Nils; Hagve, Tor-Arne; Basu, Samar; Olsen, Elisabeth; Seljeflot, Ingebjørg; Nyberg, Lena; Elind, Elisabeth; Ulven, Stine Marie (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      There is convincing evidence that consumption of fish and fish oil rich in long-chain (LC) n-3 PUFA (n-3 LCPUFA), EPA (20 : 5n-3) and DHA (22 : 6n-3) reduce the risk of CHD. The aim of the present study was to investigate whether n-3 LCPUFA-enriched food products provide similar beneficial effects as fish oil with regard to incorporation into plasma lipids and effects on cardiovascular risk markers. ...
    • Intake of fermented dairy products induces a less pro-inflammatory postprandial peripheral blood mononuclear cell gene expression response than non-fermented dairy products: A randomized controlled cross-over trial 

      Rundblad, Amanda; Holven, Kirsten Bjørklund; Øyri, Linn Kristin Lie; Hansson, Patrik; Ivan, Ingvild Hansen; Gjevestad, Gyrd Omholt; Thoresen, Magne; Ulven, Stine Marie (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-25)
      <i>Scope</i> - It is aimed to investigate how intake of high‐fat meals composed of different dairy products with a similar fat content affects postprandial peripheral blood mononuclear cell (PBMC) expression of inflammation‐related genes, as well as circulating inflammatory markers and metabolites.<p> <p><i>Methods and results</i> - Healthy subjects (<i>n</i> = 47) consume four different high‐fat ...
    • Intake of Fermented Dairy Products Induces a Less Pro‐Inflammatory Postprandial Peripheral Blood Mononuclear Cell Gene Expression Response than Non‐Fermented Dairy Products: A Randomized Controlled Cross‐Over Trial 

      Rundblad, Amanda; Holven, Kirsten Bjørklund; Øyri, Linn Kristin Lie; Hansson, Patrik; Ivan, Ingvild Hansen; Gjevestad, Gyrd Omholt; Thoresen, Magne; Ulven, Stine Marie (Journal article; Tidsskriftartikkel; Peer reviewed, 2020)
      Scope: It is aimed to investigate how intake of high-fat meals composed of different dairy products with a similar fat content affects postprandial peripheral blood mononuclear cell (PBMC) expression of inflammation-related genes, as well as circulating inflammatory markers and metabolites.<p>Methods and results: Healthy subjects (n = 47) consume four different high-fat meals composed of either butter, ...
    • Postprandial changes in gene expression of cholesterol influx and efflux mediators after intake of SFA compared to n-6 PUFA in subjects with and without familial hypercholesterolemia: secondary outcomes of a randomized controlled trial 

      Øyri, Linn Kristin Lie; Narverud, Ingunn; Bogsrud, Martin Prøven; Hansson, Patrik; Leder, Lena; Byfuglien, Marte Gjeitung; Veierød, Marit Bragelien; Thoresen, Magne; Ulven, Stine Marie; Holven, Kirsten Bjørklund (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-13)
      The long-term cholesterol-lowering effect of replacing intake of SFA with PUFA is well established, but has not been fully explained mechanistically. We examined the postprandial response of meals with different fat quality on expression of lipid genes in peripheral blood mononuclear cells (PBMC) in subjects with and without familial hypercholesterolaemia (FH). Thirteen subjects with FH (who had ...
    • Profiling of immune-related gene expression in children with familial hypercholesterolaemia 

      Narverud, Ingunn; Christensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Rundblad, Amanda; Aukrust, Pål; Espevik, Terje; Bogsrud, Martin Prøven; Retterstøl, Kjetil; Ueland, Thor; Halvorsen, Bente; Holven, Kirsten Bjørklund (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-21)
      <i>Background</i> - Innate and adaptive immune responses are pivotal in atherosclerosis, but their association with early‐stage atherosclerosis in humans is incompletely understood. In this regard, untreated children with familial hypercholesterolaemia may serve as a human model to investigate the effect of elevated low‐density lipoprotein (LDL)‐cholesterol.<p><p> <i>Objectives</i> - We aimed ...
    • Protocol and description of literature searches for the risk-benefit assessment of fish in the Norwegian diet. The Steering Committee of the Norwegian Scientific Committee for Food and Environment 

      Andersen, Lene Frost; Berstad, Paula; Carlsen, Monica Hauger; Dahl, Lisbeth; Goksøyr, Anders; Knutsen, Helle Katrine; Kvestad, Ingrid; Lillegaard, Inger Therese Laugsand; Mangschou, Bente; Meyer, Haakon E; Nauta, Maarten; Rakkestad, Kirsten Eline; Rasinger, Josef Daniel; Skeie, Guri; Starrfelt, Jostein; Thomsen, Sofie; Ulven, Stine Marie; Agdestein, Angelika; Bodin, Johanna Eva; Elvevoll, Edel O.; Hessen, Dag Olav; Husøy, Trine; Krogdahl, Åshild; Nilsen, Asbjørn Magne; Skjerdal, Olaug Taran; Steffensen, Inger-Lise Karin; Strand, Tor A; Velle, Gaute; Wasteson, Yngvild; Hemre, Gro Ingunn; Vandvik, Vigdis; Alexander, Jan (Research report; Forskningsrapport, 2020)
      Fish contains nutrients that are positive for our health. At the same time, it contains varying levels of undesirable substances that can have a negative effect on health. Undesirable substances can be found in different levels in most types of food. In a risk-benefit assessment, both the nutrients and the undesirable substances are assessed and it is evaluated whether it in total gives a more ...